{"id":207401,"date":"2024-10-19T13:21:19","date_gmt":"2024-10-19T13:21:19","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/astm-e1073-3\/"},"modified":"2024-10-25T06:02:41","modified_gmt":"2024-10-25T06:02:41","slug":"astm-e1073-3","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/astm\/astm-e1073-3\/","title":{"rendered":"ASTM-E1073"},"content":{"rendered":"

ASTM E1073-01-Reapproved2005<\/h3>\n

Withdrawn Standard: Standard Test Method for Obtaining a Pharmacological Profile with Mice (Withdrawn 2010)<\/h4>\n
\n

ASTM E1073<\/h4>\n

Scope<\/strong><\/p>\n

1.1 This test method is designed as a simple and inexpensive initial screening procedure for new compounds with unknown pharmacological properties, or for the comparative bioassay of new members of a chemical series with class reference standards. The test method, which is applicable to most pharmacologically active compounds including pesticides, will properly rank order both acute lethality and potency with a minimum expenditure of test material. It is intended as the first step in a multi-tiered development program.<\/p>\n

1.2 This standard does not purport to address the safety problems associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.<\/i><\/p>\n

Keywords<\/strong><\/p>\n

chemicals; ED50; LD50; manipulative tests; MED50; mice; nonmanipulative tests; pesticides; phamacology; toxicity<\/p>\n

ICS Code<\/strong><\/p>\n

ICS Number Code 11.120.01 (Pharmaceutics in general)<\/p>\n

DOI:<\/strong> 10.1520\/E1073-01R05<\/p>\n<\/div>\n

PDF Catalog<\/h4>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
PDF Pages<\/th>\nPDF Title<\/th>\n<\/tr>\n
1<\/td>\nScope
Summary of Test Method
Significance and Use
Apparatus <\/td>\n<\/tr>\n
2<\/td>\nSolvents
Test Solutions
Test Animals
Procedure
FIG. 1 <\/td>\n<\/tr>\n
3<\/td>\nFIG. 2
FIG. 3 <\/td>\n<\/tr>\n
4<\/td>\nFIG. 4 <\/td>\n<\/tr>\n
5<\/td>\nObservations
FIG. 5 <\/td>\n<\/tr>\n
6<\/td>\nQuality Assurance
Data Recording <\/td>\n<\/tr>\n
7<\/td>\nStatistical Evaluation of Results
Report
TABLE 1 <\/td>\n<\/tr>\n
8<\/td>\nPrecision and Bias
Keywords <\/td>\n<\/tr>\n
9<\/td>\nX1. SAMPLE DATA SHEET FOR ETONITAZINE HYDROCHLORIDE <\/td>\n<\/tr>\n
11<\/td>\nX2. SAMPLE DATA SHEET FOR CHLORPROMAZINE <\/td>\n<\/tr>\n
12<\/td>\nREFERENCES <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

E1073-01(2005) Standard Test Method for Obtaining a Pharmacological Profile with Mice (Withdrawn 2010)<\/b><\/p>\n\n\n\n\n
Published By<\/td>\nPublication Date<\/td>\nNumber of Pages<\/td>\n<\/tr>\n
ASTM<\/b><\/a><\/td>\n2005<\/td>\n13<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":207406,"template":"","meta":{"rank_math_lock_modified_date":false,"ep_exclude_from_search":false},"product_cat":[166,2637],"product_tag":[],"class_list":{"0":"post-207401","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-11-120-01","7":"product_cat-astm","9":"first","10":"instock","11":"sold-individually","12":"shipping-taxable","13":"purchasable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product\/207401","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media\/207406"}],"wp:attachment":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media?parent=207401"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_cat?post=207401"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_tag?post=207401"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}