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ASTM-E1163:2002 Edition

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E1163-98(2002) Standard Test Method for Estimating Acute Oral Toxicity in Rats

Published By Publication Date Number of Pages
ASTM 2002 3
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1.1 This test method determines the lethality (LD50 value) and signs of acute toxicity from a material using a limited number of rats. The technique used in this test method is referred to as the ‘Up-and-Down Procedure.’ This test method is an alternative to the classical LD50 test and is applicable to both liquids and solids.

1.2 This test method is not recommended for test materials which typically produce deaths beyond 2 days postdosing.

1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

PDF Catalog

PDF Pages PDF Title
1 Scope
Referenced Documents
Terminology
Summary of Test Method
Significance and Use
2 Apparatus
Test Animals
Pretest Conditioning
Sample Preparation
Procedure
Test Options
Calculation of Results
3 Report
Precision and Bias
Keywords
ASTM-E1163
$35.75