ASTM-E1619:2003 Edition

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E1619-95(2003) Standard Test Method for Chronic Oral Toxicity Study in Rats

Published By	Publication Date	Number of Pages
ASTM	2003	5

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Categories: 11.100.30 - Analysis of blood and urine, ASTM

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Description

ASTM E1619-95-Reapproved2003

Historical Standard: Standard Test Method for Chronic Oral Toxicity Study in Rats

ASTM E1619

Scope

1.1 This test method covers a long-term study to determine the effects of a substance in a mammalian species such as the rat following prolonged and repeated oral exposure. Under the conditions of the chronic toxicity test, effects that require a long latency period or that are cumulative should become manifest.

1.2 This test method assumes that the user is knowledgeable in mammalian toxicology and related pertinent areas, and relies heavily on the judgment of the evaluator.

1.3 The values stated in SI units are to be regarded as the standard. The inch-pound units given in parentheses are for information only.

This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use. For specific hazard statements, see Section 6.

Keywords

blood chemistry; chronic toxicity; feed efficiency; gavage; hematology; LD; mecropsy; oral; pesticide; rat; toxicity; urinalysis

ICS Code

ICS Number Code 11.100.30 (Analysis of blood and urine)

DOI: 10.1520/E1619-95R03

PDF Catalog

PDF Pages	PDF Title
1	Scope Referenced Documents Terminology Summary of Test Method
2	Significance and Use Hazards Facilities Test Animals Diets Range-Finding Study
3	Procedure
4	Interpretation of Results Report Quality Assurance Precision and Bias Keywords

Additional information

Standard Title	E1619-95(2003) Standard Test Method for Chronic Oral Toxicity Study in Rats
Published Code	ASTM
Publication Date	2003
Pages Count	5
ICS Codes	11.100.30 - Analysis of blood and urine